LYHN ESTHER NMN PHYTOS 2X

Effect

- Prevention of Aging and Cancer

- Helps Improve Vitality and Focus

Net Contents

10.11 g (337 mg x 30 sheets)

Quantity per Carton

200

Ingredients & Contents  

Broccoli NMN Mixed Powder [Broccoli Extract Powder (US), Mixed Agent (Tapioca Starch, Maltodextrin)] 40.66%, Pullulan, Lemon Juice Powder [Dextrin, Lemon Juice (100% Lemon; US), Arabic Gum, Citric Acid, Flavor], SirtuEnMN® Powder [Blueberry Pterostilbene Mixed Powder (Blueberry Extract 100%; US), Quercetin, Barberry Fruit Berberine Powder (Indian Barberry Fruit Extract Powder; India), Apigenin Complex, Broccoli Extract Powder] 8.94%, Pineapple Juice Powder, Flavor (Natural Lemon Flavor), Glycerin, Enzyme-Treated Stevia, Citric Acid, MCT Powder, Polysorbate 80, Nicotinamide, β-Cyclodextrin, Hydroxypropylmethylcellulose, Myricel Rice Bran Extract, Betaine, Food Coloring Blue No. 1 (Colorant)

Precautions for Consumption

Consume immediately after opening. 

Due to the nature of the product, slight color changes, bubbles, breakage, cracking, or clumping may occur, but the product is not defective. 

Individuals with unique or allergic constitutions may experience hypersensitivity reactions, so please check the ingredients before consumption. 

Be careful when opening the product as the packaging may cause injury.

Intake Amount & Method

Place on the roof of your mouth and slowly dissolve for consumption.

Expiration Date 

36 months from the date of manufacture

Main Ingredient

① Broccoli NMN: The Direct Precursor for NAD+ Synthesis, Activating Longevity Gene SIRTUIN by Increasing NAD+ Levels

- NMN (Nicotinamide Mononucleotide) is the direct precursor for NAD+ synthesis, and it has been confirmed that oral intake of NMN increases NAD+ levels in the human body.

- What is NAD+? NAD+ is a coenzyme that exists in all cells in the body and regulates bodily functions through oxidation-reduction reactions.

1) Activate SIRTUIN genes

2) Repair DNA damage

3) Regulate telomere length

4) Promote energy production in the mitochondria, helping the body function normally and preventing aging.

- This ingredient, introduced by Harvard Medical School’s David Sinclair, a leading expert in the aging field, has gained global recognition.

- NAD+ Levels Decline with Age: In people in their 50s, NAD+ levels decrease to less than half of those in their 20s.

1. Accelerated aging

2. Increased cancer risk

3. Reduced energy

4. Increased risk of degenerative muscle and neurological diseases

- Mechanisms of NAD+ in the Body

1) Coenzyme for Energy Production: NAD+ is utilized in processes to derive energy from glucose and break down fat for energy.

2) Consumption by SIRTUIN: 1. Cellular homeostasis and apoptosis 2. Gene stability 3. Insulin metabolism regulation

3) Consumption by PARP Enzyme: 1. DNA damage repair 2. Monoadpylation to bind damaged DNA

4) Regulation of Telomere Length: When telomeres shorten and unravel, genetic codes may be misinterpreted, leading to cell transformation or death.

- Blend Content: 124mg per sheet (NMN 20%, NMN content: 24.8mg)

- Raw Material Documentation: US origin, Purity: 20%

② Two Key Ingredients That Inhibit Overactivation of PARP/NADase and Help NAD+ Be Consumed by SIRTUIN: Quercetin, Apigenin, Berberine (Barberry Extract Powder)

- These ingredients help ensure that the NAD+ increased by NMN is consumed 100% by the longevity gene SIRTUIN.

- SIRTUIN, PARP enzyme, and NADase are key coenzymes that compete to consume NAD+.

- Abnormal activation of PARP and NADase (CD38, CD157, SARM-1) can worsen aging. For the benefits of a longevity supplement to be effective, the NAD+ increased by NMN should be consumed by SIRTUIN, not PARP/NADase.

- Mechanisms

① Quercetin: 1) Reduces overactivation of PARP 2) Lowers NF-kb (inflammatory transcription factor) levels

② Apigenin: 1) Reduces overactivation of PARP 2) Reduces overactivation of CD38/CD157

③ Berberine: 1) Reduces overactivation of SARM 2) Stimulates SIRTUIN through AMPK enzyme activation

- Blend Content: Blended at clinical levels for human use, with 5%-10% of the dosage: Quercetin: 12.5mg, Apigenin: 1mg, Berberine: 0.1mg

③ Synergistic Ingredients for Promoting SIRTUIN Activation: Pterostilbene, Quercetin, Apigenin + Betaine + Vitamin D

- Various phytochemicals have been studied for activating SIRTUIN, and ingredients with high evidence supporting their effectiveness have been selected and combined.

- Mechanisms

1. Pterostilbene: 1) The active form of resveratrol 2) Resveratrol increases SIRT1 activation by more than 8 times

2. Quercetin: 1) Activates SIRT1 2) Reduces NF-Kb (inflammatory transcription factor) levels

3. Apigenin: 1) Activates SIRT1 2) Reduces overactivation of PARP/NADase

4. Berberine: 1) Activates SIRT1 2) Activates Nrf-2 (antioxidant transcription factor) 3) Stimulates AMPK enzyme

5. Betaine: 1) A basic component for methylation 2) Supports DNA stabilization

6. Vitamin D: 1) A fundamental component for immune health 2) Improves insulin resistance through SIRT1 activation

- Blend Content: Blended at clinical levels for human use, with 5%-10% of the dosage: Pterostilbene: 12.5mg, Quercetin: 12.5mg, Apigenin: 1mg, Betaine: 1mg, Berberine: 0.1mg, Vitamin D: 1mg, Vitamin B3: 4.5mg

④ Ingredient to Promote Autophagy: Spermidine

- Autophagy is a critical system in the human body, awarded the Nobel Prize in Physiology or Medicine in 2016, that recycles cellular waste to maintain normal body function.

- Spermidine directly stimulates autophagy, and its final product, spermin, is utilized in autophagy processes.

- Studies in cells and animals have confirmed that spermidine extends lifespan.

- Blend Content: 1mg (1% Spermidine)

Selling Point

① All ingredients necessary for increasing NAD+ and activating SIRTUIN are contained in one sheet.

- The decrease in NAD+ levels due to aging leads to reduced energy production in the mitochondria, which accelerates aging and cancer development.

- NAD+ is competitively consumed by 1. SIRTUIN 2. PARP 3. NADase (CD38, CD157, SARM-1).

- Reducing the overactivation of PARP/NADase and increasing the activity of SIRTUIN can activate various genes that help keep the biological age healthy.

- This product is formulated considering three mechanisms: 1) Precursor substance for NAD+ 2) Reduction of overactivation of PARP/NADase 3) Activation of SIRTUIN

 · Increased NAD+ concentration: Increases NAD+ levels in the body through the intake of naturally derived NMN and vitamin B3.

 · Reduction of overactivation of PARP/NADase: Through quercetin, apigenin, and berberine, NAD+ is consumed 100% by SIRTUIN.

 · Activation of SIRTUIN: Promotes SIRTUIN activation through pterostilbene, quercetin, apigenin, betaine, and vitamin D.

② Optimal Ingredient for Increasing NAD+ Concentration: NMN

- Several ingredients, such as tryptophan, niacin, niacinamide, and NR, have been studied to increase NAD+ levels, but it has been confirmed that NMN is the closest substance to NAD+ in the human synthesis process, effectively raising NAD+ concentration.

- By increasing NAD+ levels through NMN, you gain 1) SIRTUIN activation 2) PARP enzyme (DNA repair) 3) Telomere length regulation 4) Mitochondrial energy production.

  These four key benefits can help reverse biological age by over 10 years and maintain the vitality and focus of your 20s.

 Safely consume with naturally derived NMN

- The number one recommended ingredient by Harvard Medical School professors.

③ The number one recommended ingredient by Harvard Medical School professors.

- It was once believed that simply increasing NAD+ levels would activate SIRTUIN, but recent research has shown that the overactivation of PARP and NADase interferes with SIRTUIN's consumption of NAD+, promoting aging and cancer.

- Quercetin, apigenin, and berberine help inhibit the overactivation of PARP/NADase, allowing NAD+ to be consumed by SIRTUIN.

- Betaine contributes to DNA stabilization through methylation, while pterostilbene activates SIRT1, acting as a synergistic ingredient.

- Four phytochemical ingredients to achieve the ultimate goal of SIRTUIN activation

- Enjoy numerous health benefits with naturally derived phytochemicals.

④ Spermidine, which promotes autophagy and cleanses waste in the body

- Autophagy is a vital system in the body that won the Nobel Prize in Physiology or Medicine in 2016. It recycles waste to maintain the body in a healthy state.

- In related cell and animal studies, spermidine administration has been shown to have lifespan-extending effects.

Recommended Target

- Those who want to prevent aging and cancer with one sheet a day.

- Those who want to reverse their biological age by 10 years or more and regain the vitality and focus of their 20s with one sheet a day.

- Those who want to consume the elixir of immortality and youth in the form of a film in the 21st century.

- Those who want to maintain a healthy body by consuming a variety of phytochemicals.

- Those who want to consume a real NMN product with noticeable effects.