DR. ESTHER COLLAGEN BIOTIN PLUS

Daily Intake: 2 packets (4 g)

※ % Nutritional Value: Percentages of the daily nutritional value

1. What is Gly-Pro-Val-Gly-Pro-Ser?
– 1. Gly-Pro-Val-Gly-Pro-Ser (Glycine-Proline-Valine-Glycine-Proline-Serine)
– It is the indicative component of “Fish Collagen Peptide,” which is extracted from the scales of tilapia fish. It contains 92% of fish collagen peptide. (It has been confirmed that its consumption significantly increases the concentration in the bloodstream compared to fish scales.)

2. Fish Collagen Peptide
– Customized formulation – Functional Content: Can help maintain skin health against damage from UV rays and provide skin moisturization.
– High absorption fish scale collagen peptide with two human trials and two animal experiments.
– In human trials, five skin improvement effects are confirmed: significant increase in elasticity, significant increase in moisture content, significant wrinkle improvement, significant reduction in skin roughness, and significant reduction in transepidermal water loss.
– In animal experiments, three effects are confirmed: significant reduction in skin redness, significant increase in collagen content, and significant reduction in collagen degradation.
– The source of collagen is from Nitta Gelatin, the leader in the field with 100 years of expertise.
– Proven ingredients in terms of safety (processed exclusively under controlled conditions using safe traceable materials), efficacy (demonstrated through various clinical trials), and quality (high-quality collagen peptides through a dual purification process).
* Each daily dose contains 3,270mg of fish collagen peptide.

3. Biotin
– Required for carbohydrate, fat, protein metabolism, and energy production.
– Acts as a coenzyme for the four carboxylases involved in glucose synthesis, fatty acid synthesis, and amino acid metabolism.
– Promotes the three major nutrient metabolisms to provide nourishment and regeneration to the skin and scalp, playing an important role in skin and hair health.
– According to the Korean Dietary Reference Intakes for Koreans (2015) by the Ministry of Health and Welfare, 89.5% of Koreans are reported to consume insufficient biotin.

4. Vitamin A
– Increases collagen synthesis by increasing the mRNA of procollagen type 1 and type 3
[Source: Journal of Investigative Dermatology, 2000, 114: 480-486 (SCIE)]

5. Vitamin C
– Promotes collagen synthesis by activating enzymes necessary for the collagen synthesis process.
It activates essential enzymes (lysyl and prolyl hydroxylase) required during the collagen synthesis process to enhance collagen cross-link synthesis.
[Source: International Journal of Cosmetic Science, 1998, 20: 151-158 (SCIE)]

1) Contains 3,270mg of Fish Collagen Peptide, individually recognized for its functionality by the Ministry of Food and Drug Safety.
– Conveniently supports skin health with 2 sachets a day.
– Functionality: Can help maintain skin health against damage from UV rays and provide skin moisturization.

2) Contains elastin and hyaluronic acid, which are components of the skin’s dermis, along with collagen.

3) We’ve also included biotin, which can aid in carbohydrate, fat, and protein metabolism and energy production.
– Biotin is included at 4,000% of the daily recommended intake level.
– Biotin is a water-soluble vitamin recognized for its functionality in supporting carbohydrate, protein, and fat metabolism, as well as aiding in energy production in the body.
– Biotin is commonly known for its role in nourishing skin, hair, and nail regeneration.
– Since a deficiency in biotin can hinder collagen synthesis, it is advisable to ensure an adequate intake of biotin.

4) We’ve combined vitamin C, an essential component in collagen synthesis.
– Recognized by the Ministry of Food and Drug Safety for functionality related to “formation of connective tissue and maintenance of function” and “necessary for antioxidant action to protect cells from harmful oxygen.”
– When protein peptides broken down and absorbed by digestive enzymes are re-synthesized into collagen protein fibers in the body, vitamin C acts as a cofactor.
– Glycine, lysine, and proline are essential amino acids for collagen synthesis.
– Hydroxylation (the addition of -OH groups) is required for lysine and proline to be synthesized into collagen proteins.
– Vitamin C is needed for the hydroxylation process.
– Hydroxylated lysine and proline form hydrogen bonds (-HO ···· OH-), creating cross-links and producing robust collagen protein.

5) Ingredient blending expertise of Dr. LYUH ESTHER.
– Dr. LYUH ESTHER: Preventive medicine doctor at Seoul National University, specialist in family medicine.

6) Hygienic and convenient packaging for easy consumption.
– Each stick is individually packaged within the case, ensuring safety and convenient intake.

Those who are concerned about skin damage due to year-round exposure to UV radiation
Those who wish to receive assistance with moisturization due to dry skin
Those who are exposed to strong UV radiation in their professions
Those who want to maintain overall skin health
Middle-aged or elderly people who want to receive help with elasticity and moisturization due to skin aging