DR.ESTHER LACTIUM PLUS

Daily Intake: 2 tablets (1,600mg)

※ % Nutritional Value: Percentages of the daily nutritional value

1. Lactium (Milk Protein Hydrolysate)
– A physiologically active protein peptide created by hydrolyzing casein protein, one of the milk proteins.
– It acts on GABA receptors and has the functional claim of “helping improve sleep quality.”
– It aids in nervous system stability, stress relief, and alleviating insomnia.
* Note: Milk contains protein and tryptophan, which are rich in serotonin, a neurotransmitter related to mood, and the precursor to melatonin, which is related to the body’s biological clock.

2. GABA (γ-AminoButyric Acid)
– The body’s primary inhibitory neurotransmitter present in the central nervous system.
– Increases the relaxed state of the brain’s activity, known as alpha waves, and decreases beta waves associated with stress and anxiety.
– One of GABA’s most important functions is to alleviate stress and anxiety.

3. St. John’s Wort Extract Powder
– Contains an ingredient called hypericin that inhibits serotonin-degrading enzymes.
– Suppresses the secretion of stress hormones, has calming effects, and acts on receptors related to anxiety, depression, and sleep disorders.
– Also exhibits similar actions to female hormones and can be used for menopausal symptoms.

4. Evening Primrose Extract
– Contains the compound harmine, which has calming effects and induces mild euphoria. It is used as a relaxant and analgesic.

5. Tryptophan
– An essential amino acid necessary for the production of serotonin, melatonin, and vitamin B3 (niacin).
(Tryptophan -> Serotonin -> Melatonin)

6. Montmorency Tart Cherry
– Abundantly contains melatonin, a hormone responsible for regulating the biological clock.
– Melatonin is primarily secreted in the brain during the night and contributes to the recovery of the biological clock.

7. Saccharomyces cerevisiae Yeast
– A type of yeast used in the brewing of beer.
– Increases the activation of the adenosine A2A receptor, which induces deep sleep with increased delta waves, enhancing sleep quality.
– Promotes the secretion of growth hormone during sleep, which strengthens the immune system, increases muscle mass, and promotes bone formation.

1. Individual Recognized Functional Ingredient – Milk Protein Hydrolysate (Lactium)
– A physiologically active protein peptide created by hydrolyzing casein protein, one of the milk proteins.
– Each daily intake contains 300mg of individual recognized milk protein hydrolysate (Lactium), making it easy to consume in small quantities.
– Functionality: It can help improve sleep quality (Individual Recognition No: 2020-2).
– Produced using exclusive ingredients from France’s Ingredia, a global dairy processing specialist with a history of over 70 years.
– Collaborative research with the Sleep Center at Ewha Womans University Mokdong Hospital.
– Developed through several years of research and development, with over 7 SCI-level papers related to Lactium published.
– The 36th individual recognized ingredient produced by NovaRx, an R&D specialized company, using their technical expertise and know-how.
– Human application trial: 96 participants took 300mg/day of Lactium (milk protein hydrolysate) for 4 weeks. Resulted in increased total sleep time and sleep efficiency, as well as decreased sleep latency and wake time during sleep.
– Improved sleep efficiency was observed both subjectively (based on sleep diary, psychological level) and objectively (based on actigraphy, physiological level), indicating better perceived sleep quality.
**Actigraphy: A portable device worn on the wrist to measure sleep states.
– Registered with the U.S. FDA NDI (New Dietary Ingredient) (NDI no. 242) as a safe ingredient.

2. Dr. LYUH ESTHER’s Expertise in Ingredient Formulation
– Dr. LYUH ESTHER: Preventive Medicine Doctor, Family Medicine Specialist, Seoul National University Medical College

Those who have recently become more sensitive and find it difficult to fall asleep
Those who sleep but don’t feel refreshed
Those who want to wake up to a comfortable and refreshed morning
Those who want to prioritize quality sleep over quantity