LYUH ESTHER LIPOSOME GLUTATHIONE DIRECT ULTRA X

2. Skin whitening

3. Anti-aging

1. Glutathione absorption rate enhancement Oral Dissolving Film (ODF)

   – Oral dissolving refers to the method of directly absorbing functional ingredients into the capillaries through the oral mucosa.

   – Since it bypasses digestive metabolism, there is less loss of functional ingredients, and the absorption rate in the body is fast, making it suitable for emergency medications such as angina emergency treatments.

   – Especially, the oral submucosa has about 4,000 times the permeability compared to the epidermis and is suitable for the application of water-soluble low-molecular substances.

   * Studies on the application of glutathione through the oral mucosa have been reported.

2. Supply of glutathione in the body: Glutathione with 90% purity (sourced from the Netherlands)

   – Glutathione is a powerful antioxidant synthesized in the cell from the combination of three amino acids (glutamate, cysteine, glycine).

   – It acts as a powerful antioxidant within cells and is used as a medication for liver toxicity and drug poisoning.

   – It inhibits tyrosinase involved in melanin synthesis, aiding in skin whitening and is a major ingredient in glutathione injections.

   – It is involved in antioxidant and metabolic processes in the body and offers benefits in detoxification, antioxidant, anti-inflammatory, liver cell protection, cytotoxic protection, and prevention of aging and dementia.

2.1 Stability & absorption rate UPGRADE through liposome formulation technology!

   – Liposome: A small sphere with a double-layer lipid structure designed to safely transport substances from outside to inside the body.

   – Liposome formulation technology is applied to stabilize glutathione and increase bioavailability.

   – Contains 90% pure glutathione sourced from the Netherlands.

3. Promotion of glutathione synthesis in the body: L-Cysteine

   – [L-Cysteine]: An amino acid containing sulfur (S), L-cysteine is a precursor to glutathione synthesis in cells and is essential for the synthesis of glutathione.

   * L-Cysteine is typically consumed in lesser amounts in the diet compared to other amino acids needed for glutathione synthesis, such as glutamate and glycine.

   – L-Cysteine promotes the synthesis and metabolism of glutathione and acts in skin whitening (inhibition of melanin pigmentation).

4. Inhibition of glutathione depletion in the body: Vitamin C, Vitamin E, Milk Thistle

4.1. Vitamin C

   – Vitamin C is an exogenous antioxidant that forms a non-enzymatic antioxidant system in cells with glutathione and vitamin E.

   – It helps sustain antioxidant actions by reducing oxidized vitamin E.

   – An increase in glutathione levels in red blood cells following vitamin C supplementation has been observed.

4.2. Vitamin E

   – Vitamin E is an exogenous antioxidant that forms a non-enzymatic antioxidant system with glutathione and vitamin C.

   – It inhibits oxidation of the cell membrane by reactive oxygen species, and deficiency can lead to easy oxidation and cell damage.

   – An increase in glutathione levels in red blood cells following vitamin E supplementation has been observed.

4.3. Milk Thistle

   – Contains silymarin, which acts in the phase I of liver detoxification and functions as a strong antioxidant and liver toxicity protector.

   – It is presumed to compete with glutathione for consumption in the body, confirming mechanisms that enhance glutathione.

   – It has detoxifying, lipid peroxidation inhibiting, and antioxidant effects, with additional benefits in improving skin erythema and whitening.

1. Systematic formulation design for the efficient absorption and utilization of glutathione, the key ingredient in glutathione injections:

1) Reduced glutathione formulation for direct supply of glutathione:

     – Confirmed benefits in detoxification, antioxidant, anti-aging, and whitening.

     – Yeast extract liposomal glutathione with 90% purity considering body absorption rate.

     – Liposomal form of glutathione wrapped in phospholipids, with low exposure risk to external hazards.

2) L-cysteine formulation to enhance glutathione synthesis:

     – Research reports confirm L-cysteine’s promotion of glutathione synthesis and whitening effects.

3) Vitamin C, Vitamin E, and milk thistle formulation to inhibit glutathione depletion:

     – Research reports confirm an increase in glutathione levels following Vitamin C supplementation.

     – Research reports confirm an increase in glutathione levels following Vitamin E supplementation.

     – Research reports confirm the mechanism of glutathione enhancement following milk thistle (silymarin) intake.

2. Synergistic formulation that incorporates the core components of the intracellular non-enzymatic antioxidant system:

   – The intracellular non-enzymatic antioxidant system follows the chain [Glutathione → Vitamin C → Vitamin E].

   *After antioxidant activity, oxidized Vitamin E is reduced by Vitamin C, and oxidized Vitamin C is reduced by glutathione.

   – The combination of glutathione, Vitamin C, and Vitamin E aims for efficient antioxidant activity.

3. 2-in-1 ingredient setting that achieves both antioxidant and skin beauty:

   – Four core ingredients reported to have benefits in antioxidants & skin whitening: Glutathione, L-Cysteine, Vitamin C, Vitamin E.

4. Rapid and loss-free delivery of functional ingredients through oral dissolving film:

   – Direct delivery of functional ingredients through the oral mucosa, which has about 4,000 times the permeability of the epidermis.

   – Little loss of nutrients and fast absorption since it bypasses the digestive metabolism process.

5. Review of ingredient formulation and bioavailability by Dr. LYUH Eshter:

   – Dr. LYUH Eshter: Preventive Medicine Ph.D. from Seoul National University, Specialist in Family Medicine.

   – Review of the nutritional and preventive medical significance and safety of product formulation.

   – Comparison of action mechanisms and review of bioavailability with glutathione intravenous injections prescribed in family medicine.

6. Individual packaging & convenient portability and intake to prevent oxidation of functional ingredients:

   – Individual film packaging inside the case to prevent oxidation of functional ingredients and enhance portability.

   – Enhances convenience of intake with a refreshing lemon scent when attached to the oral mucosa.

Those looking for a glutathione product with enhanced absorption in film form.

Those seeking food that supports liver health and antioxidant activity.

Those desiring skin whitening through antioxidant action.

Those wanting a brighter skin tone due to melasma or pigmentation issues.

Those looking for a glutathione product that the whole family can consume.