LYUH ESTHER ELASTIN SUPER ACTIVE 2.0

2. Restrain breast sagging

3. Improves ligament function

Daily Intake: 1 tablet (400mg)

※ % Nutritional Value: Percentages of the daily nutritional value 

[Ministry of Food and Drug Safety Functional Evaluation Guide: Skin Health Section]

1. Causes of Skin Aging

   ① Intrinsic Aging:

   – Definition: Decreased fibroblast activity and cell count (collagen, elastin, fibrillin, etc.) due to aging.

   – Major Symptoms: Fine wrinkles, skin dryness, reduced elasticity.

   ② Extrinsic Aging:

   – Definition: Skin damage due to UV exposure.

   – Process: UV exposure → Activation of reactive oxygen species and inflammatory responses →

     ① Activation of AP-1 leads to decreased synthesis of dermal collagen type 1 & 3.

     ② Activation of AP-1, NF-kB: Activation of MMP1, 3, 9 leads to degradation of dermal tissue (reduced collagen, elastin).

   ③ Causes and Process of Wrinkle Formation:

   – Aging or skin damage due to UV exposure stimulates AP-1, leading to the breakdown of dermal tissue.

   *AP-1 regulates the expression of many genes related to cell proliferation and differentiation and strongly controls the expression of some MMPs.

   – MMP-1 is collagenase 1, which degrades collagen type 1 & 3.

   – MMP-3 degrades collagen type 4 and activates pro-MMP-1.

   – MMP-9 further breaks down products degraded by collagenases into smaller fragments.

   → Collagenases (collagen-degrading enzymes) and elastinases (elastin-degrading enzymes) induced by skin damage reduce dermal constituents and disrupt skin tissue.

2. Ingredients to Consider for Consumption:

   – Dermal components (collagen, elastin, hyaluronic acid), epidermal components (ceramides).

   – Antioxidant ingredients (vitamin C, vitamin E).

   – Ingredients that can inhibit collagenases/elastinases.

① Biotin: The Basic Vitamin for Improving Hair and Skin Health

– Biotin is a vitamin essential for the metabolism of carbohydrates, proteins, and fats.

  Deficiency can lead to various conditions, including hair loss, discoloration, skin inflammation, conjunctivitis, rashes, and central nervous system abnormalities like depression and hallucinations.

– [Human Trial] Results of administering 10mg/1 day of biotin to 30 patients experiencing side effects of acne treatment showed an increase in hair growth.

  https://pubmed.ncbi.nlm.nih.gov/33682085/

– [Human Trial] Providing 4-5mg/1 day of biotin to children with atopic dermatitis resulted in improved dryness and itching.

  https://sci-hub.se/https://pubmed.ncbi.nlm.nih.gov/29438761/

– Formulation content: 100% RDA (Recommended Daily Allowance)

② Salmon Milt Extract DNA-NA (SALMON MILT EXTRACT): An Innovative Ingredient for Skin Regeneration and Anti-Aging

– Nucleic acids consist of DNA, which carries information for creating cells, and RNA, which synthesizes necessary proteins based on DNA information.

– Consuming nucleic acids, abundant in seafood and meat, is known to have effects such as [skin beauty, fatigue recovery, immune enhancement, improved brain function].

– Salmon DNA is an innovative ingredient for skin regeneration and anti-aging, and when consumed at 1g/1 day, it has been shown to reduce age spots, wrinkles, and overall skin quality in human trials.

– [Human Trial] Results of providing 1,000MG/1 day for 4 weeks to 7 men aged 40-60 showed overall improvement in skin quality (reduced age spots, wrinkles, and decreased pore count).

– [Human Trial] Applying a 3% DNA cream to the skin of 10 men aged 30-50 resulted in improved skin hydration and elasticity.

– [Animal Trial] In a study involving 14 mice induced with accelerated aging, providing a 0.1% DNA-Na-containing diet for 11 months improved the aging score (anti-aging).

③ Seven Ingredients for Skin Health

– Collagen, Hyaluronic Acid, Ceramides: The three main ingredients for the dermis and epidermis (ceramides).

  Collagen: India origin, 300 Da, ultra-low molecular weight fish collagen.

  Hyaluronic Acid: Domestic origin, microbe fermentation, purity over 90%.

  Milk Ceramide: New Zealand origin.

④ Snail Extract Powder, Rosemary Extract Powder, L-Glutathione (50%), White Tomato Powder

– Snail Extract Powder: Mucin is a mucous substance found in between the skin layers and is rich in mucous components that snails use to heal their wounds themselves.

  Source Document: France origin,

– Rosemary Extract Powder: Rosemary, also used as a recognized ingredient for skin health, contains antioxidants such as carnosic acid and lutein.

  Source Document: Domestic origin, Rosemary Raw Material (Turkey origin).

– L-Glutathione (50%): A famous whitening ingredient known for its use in intravenous injections, the most important antioxidant synthesized in the human liver.

  Source Document: India origin, 50% purity.

– White Tomato Powder: Contains substances such as phytoene and phytofluene, which absorb ultraviolet rays. It inhibits melanin pigmentation and helps with whitening.

  Source Document: U.S. origin, 5% purity of carotenoids.

① VGPG Elastin® Peptide (100mg) – The First Domestic Dual-Function Elastin for Skin Health

– This is the first and only domestically certified ingredient with desmosine and isodesmosine confirmed through an authorized analysis method. (Typically, general food ingredients rely on foreign certified agency tests)

– Acknowledged for its dual functionality in improving skin hydration and protecting against UV damage.

– Contains low-molecular-weight elastin, with molecules of 500DA or less accounting for 61% of the total.

– To produce 1g of elastin raw material, 20kg of bluefin tuna are used, making it a valuable ingredient at 0.005%.

– It takes more than 10,000 bluefin tuna to produce 1kg of elastin.

    Human trials confirmed a +39% improvement in skin hydration and a -1,744% reduction in skin wrinkles (Ra).

② Biotin 100% for Hair and Skin Health + Salmon DNA for Skin Regeneration and Anti-Aging

– Biotin is a fundamental nutrient for carbohydrate, protein, and fat metabolism and its deficiency can lead to hair loss and skin disorders.

– Salmon DNA, extracted from salmon roe, is associated with improved skin regeneration and enhanced moisture and elasticity.

    Human trials confirm the improvement of hair health and skin conditions with biotin.

    Salmon DNA consumption in human trials resulted in reduced age spots, wrinkles, pore size, and demonstrated anti-aging effects.

③ Dermis/Epidermis Components + Natural Animal/Plant-Derived Skin Health Ingredients + Key Whitening Ingredient Glutathione

– Three dermis components (Collagen, Hyaluronic Acid) + epidermis component (Milk Ceramide).

– Snail extract powder, containing mucin, a substance found in snail slime, is known for its wound healing properties and is naturally found in the skin.

– Rosemary extract powder, recognized for skin health, contains antioxidants like carnosic acid and lutein.

– White tomato powder inhibits melanin pigmentation, aiding in skin whitening.

– L-Glutathione Yeast Extract (50%), a well-known whitening ingredient, is synthesized in the human liver.

④ No Synthetic Additives

– Typically, shaping and preventing deformation is achieved through the use of synthetic additives. There are four categories:

  1) Shaping and Maintenance: Thickeners, expanders, solidifiers [Silicon Dioxide, Magnesium Stearate, Refined Dextrin, Isomalt].

  2) Prevention of Deformation and Quality Preservation: Preservatives, antioxidants [Glycerin].

  3) Maintaining Quality and Enhancing: Emulsifiers, high-quality enhancers [HPMC, Stearic Acid, Titanium Dioxide].

  4) Shape, Taste, and Odor: Coloring agents, flavor enhancers, aroma improvers.

– This product is a purified formulation without synthetic additives and instead uses ingredients like cornstarch, carnauba wax, and rice protein powder in place of synthetic disintegrants such as HPMC, magnesium stearate, and silicon dioxide.

Those who want to consume dual-functional elastin once a day,

Those who want to consume epidermis, dermis components, and premium inner beauty ingredients once a day,

Those who want to consume the first domestically recognized functional elastin approved by the Korea Food and Drug Administration,

Those who want to consume elastin that can be quality controlled through the first and only certified analysis in South Korea.