| Ingredients & Contents |
Prickly pear extract (JosincestⓇ) [Functional Ingredient Approval No. 2021-12 / Maltodextrin, Concentrated Extract of Prickly Pear Solid (Korea)], Zinc Oxide, Sodium Aselenic Acid, Vitamin D3 Compound [Vitamin D3, Arabic Gum, Sucrose, Corn Starch, Processed Fat (Palm Oil), Silicon Dioxide, Vitamin E], Crystalline Cellulose, Hydroxypropyl Methylcellulose, Carboxymethylcellulose Calcium, Silicon Dioxide, Magnesium Stearate, Stearic Acid, Glycerol Fatty Acid Ester, Vitamin K1 Compound [Arabic Gum, Vitamin K1, Sucrose], Shark Cartilage Powder (Australia), Hyaluronic Acid Compound [Trehalose, Hyaluronic Acid], Thistle Powder (Domestic), MSM (USA), Green-Lipped Mussel Powder (New Zealand), N-Acetyl Glucosamine (Origin: Thailand), Boswellia Extract Powder (India), Turmeric Extract Powder (India)
* Contains shrimp and shellfish (mussels) |
| Main Ingredient |
[Prickly Pear Extract (Josincest®)]
1. Name Origin
- The name "Josincest" is derived from the mystical prickly pear, which has nine segments. It is believed that the name "prickly pear" originated from the practice of harvesting it on September 9th of the lunar calendar, as its medicinal efficacy is considered to be most potent at that time.
- "Josincest" is a compound word derived from "Joint" (referring to joints) and "Sist" (referring to support).
2. Individual Recognized Ingredient
- Individual Recognition Number: No. 2021-12 (September 28, 2021)
- Functional Claim: It may contribute to joint and cartilage health.
- Origin: Cultivated in Jeongeup, Jeollabuk-do, South Korea.
- Key Component: Linarin 2mg (Dosage: 250 mg/day of prickly pear extract)
3. Benefits
- Supported by in vitro, in vivo, human application trials, numerous research papers, and patent data, it is confirmed to have a positive effect on improving joint and cartilage health.
- It demonstrates an effect on improving the structural and functional aspects of damaged joint tissues, which have been compromised physically and immunologically, by inhibiting the secretion of inflammatory agents and the factors responsible for cartilage tissue damage.
4. Patents and Trademark Registration
- Developed by GC Green Cross Wellbeing Comprehensive Research Institute over ten years, this ingredient has been granted two patents and registered as a trademark.
- Composition for the prevention and treatment of bone and joint diseases using prickly pear extract.
- Patent/trademark registration for a pharmaceutical composition containing stabilized natural extracts.
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| Selling Point |
1. 100% domestically sourced plant-based ingredient, Prickly Pear Extract, extracted from the leaves and stems of Prickly Pear Cactus.
- Recognized as a trusted new dietary ingredient (NDI) by the U.S. FDA (Food and Drug Administration).
- Concentrated over 2,500% more than the original prickly pear, allowing the intake of the key component, Linarin, in a single dose.
2. Prickly Pear Extract with a well-established mechanism and proven effects based on ample research data.
- Confirmed to improve joint and cartilage health through the inhibition of cytokines and inflammatory mediators responsible for joint inflammation and by increasing cartilage differentiation factors.
- Significant improvement observed in human application trials involving Koreans (110 individuals aged 40-75 with osteoarthritis) over a 12-week period. þ Improvement in overall joint-related K-WOMAC scores. þ Enhanced physical function, as indicated by K-WOMAC scores. þ Reduction in knee joint pain, according to VAS pain scores. þ Improved emotional and role function based on KSF-36 quality of life indicators. þ Increased overall well-being according to KSF-36 health status scores.
3. Convenient one-a-day intake for joint and cartilage care.
- Formulated with key ingredients for joint and bone structure, including vitamin D, zinc, and selenium.
- Contains 9 carefully selected co-ingredients for joint health: Vitamin K, shark cartilage, hyaluronic acid, Japanese knotweed, MSM, green-lipped mussel, N-acetyl glucosamine, boswellia, and turmeric.
4. Ingredient formulation expertise from Dr. Lyuh Esther
- Dr. Esther: Preventive Medicine Doctor and Family Medicine Specialist at Seoul Medical School.
- Developed ingredient combinations considering the physiological characteristics and health status of Koreans.
5. Free from 5 additives, simple and hygienic PTP packaging.
- No added saccharin sodium, synthetic flavorings, colorings, sweeteners, or polyvinylpyrrolidone. -
Contains HPMC, carboxymethylcellulose calcium, silicon dioxide, and magnesium stearate for quality stability.
- Convenient and hygienic PTP individual packaging for easy portability and storage.
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