LYUH ESTHER GLUTATHIONE DIRECT 3X

1. Improved Absorption of Glutathione through Orally Dissolving Film (ODF)
- Oral dissolving film allows functional substances to be directly absorbed into the bloodstream through the oral mucosa.
- Since it doesn't go through the digestive metabolism, it results in minimal loss of functional substances and faster absorption into the body, making it suitable for emergency medical products such as angina treatment.
- The oral mucosa has about 4,000 times the permeability compared to the epidermis, making it suitable for the application of water-soluble low molecular weight substances.
* Research results have been reported on the application of glutathione through the oral mucosa.

2. Supply of Glutathione in the Body: Glutathione (L-Glutathione 50%, from Netherland)
- Glutathione is a powerful antioxidant synthesized by the combination of three amino acids (glutamic acid, cysteine, glycine) within cells.
- It acts as a potent antioxidant inside cells and is used as a treatment for liver toxicity and drug poisoning.
- It helps with skin whitening by inhibiting tyrosinase, which is involved in melanin synthesis, and is used as a major component of intravenous injections.
- Glutathione is involved in both antioxidant and metabolism in the body, with benefits including detoxification, antioxidation, inflammation control, liver cell protection, cellular toxicity protection, and prevention of aging and dementia.

3. Promotion of Glutathione Synthesis in the Body: L-Cysteine
- [L-Cysteine]: L-Cysteine, an amino acid with sulfur (S), is an essential precursor for glutathione synthesis within cells.
* L-Cysteine is found in lower dietary amounts compared to other amino acids, such as glutamic acid and glycine, which are necessary for glutathione synthesis.
- L-Cysteine promotes glutathione synthesis, metabolism, and has a skin whitening effect (inhibiting melanin pigment production).

4. Inhibition of Glutathione Depletion in the Body: Vitamin C, Vitamin E, Milk Thistle 4.1. Vitamin C
- Vitamin C is an exogenous antioxidant that, along with glutathione and Vitamin E, forms the enzymatic antioxidant system within cells.
- It contributes to the continuous antioxidant action by recycling oxidized Vitamin E after antioxidant action.
- Supplementation of Vitamin C has been shown to increase the quantity of erythrocyte glutathione.

4.2. Vitamin E
- Vitamin E is an exogenous antioxidant that, along with glutathione and Vitamin C, forms the non-enzymatic antioxidant system.
- It inhibits cell membrane oxidation caused by reactive oxygen species in cell membranes, and insufficient Vitamin E leads to easy cell membrane oxidation and cell damage. 
- Supplementation of Vitamin E has been shown to increase the quantity of erythrocyte glutathione.

4.3. Milk Thistle
- A substance containing silymarin, which acts on phase I of the liver detoxification process as a potent antioxidant and liver-protective agent.
- It is estimated to be competitively consumed within the body as an antioxidant, thus enhancing glutathione mechanisms.
- It works as a detoxifier, inhibits lipid peroxidation, has antioxidant effects, and provides additional benefits such as improving skin redness and whitening.

1. Systematic Formulation Design for Efficient Absorption and Utilization of Glutathione, the Core Component of Whitening Injection
- A formulation of reduced glutathione with 75% purity for direct supply of glutathione through yeast extract to ensure efficient absorption and utilization.
* Confirmed benefits include detoxification, antioxidation, anti-aging, and skin whitening.
- Formulation including L-cysteine to enhance glutathione synthesis.
* Research reports confirm L-cysteine's promotion of glutathione synthesis and whitening effects.
- Formulation including Vitamin C, Vitamin E, and milk thistle to inhibit glutathione depletion.
* Research reports confirm the increase in glutathione quantity with Vitamin C supplementation.
* Research reports confirm the increase in glutathione quantity with Vitamin E supplementation.
* Research reports confirm the enhancement mechanism of glutathione with milk thistle (silymarin) intake.

2. A Synergistic Formulation Containing the Core Components of the Cellular Non-Enzymatic Antioxidant System
- The cellular non-enzymatic antioxidant system consists of a sequential system of [glutathione → Vitamin C → Vitamin E].
* Vitamin C recycles oxidized Vitamin E after antioxidation, and glutathione recycles oxidized Vitamin C.
- A formulation of glutathione, Vitamin C, and Vitamin E aims to achieve efficient antioxidation.

3. Achieving Antioxidation and Skin Beauty Simultaneously with a 2in1 Ingredient Setting
- Four core components have reported benefits in antioxidation and skin whitening.
* Glutathione, L-cysteine, Vitamin C, Vitamin E.

4. Rapid and Lossless Delivery of Functional Ingredients through Orally Dissolving Film (ODF)
-Direct delivery of functional substances through the oral mucosa, which has permeability about 4,000 times that of the epidermis.
- The process doesn't involve digestion and metabolism, resulting in minimal nutrient loss and fast absorption.

5. Review of Dr. Lyuh Esther's Formulation and Bioavailability
- Dr. Lyuh Esther: Preventive Medicine Doctor, Family Medicine Specialist at Seoul Medical School.
- Evaluation of the nutritional, preventive medicine significance, and potential risks of the product's formulation.
- Comparison and assessment of the working mechanism and bioavailability of the product with glutathione intravenous injections prescribed in family medicine.

6. Individual Packaging for Preventing Oxidation of Functional Ingredients & Convenience of Carrying and Consumption
- Individual film packaging within the case to prevent oxidation of functional ingredients and enhance portability.
- Pleasant lemon flavor upon attachment to the oral mucosa for enhanced consumption convenience.

- Those looking for foods that promote liver health and antioxidative effects. 
- Those seeking skin whitening through antioxidative effects. 
- Those desiring a brighter skin tone by addressing freckles or pigmentations. 
- Those searching for glutathione products with increased absorption in film form instead of capsules.