LYUH ESTHER GLUTATHIONE DIRECT 5X

1. Enhanced Glutathione Absorption via Orally Disintegrating Film (ODF)
- Oral disintegration enables the direct absorption of functional ingredients through the oral mucosa into the bloodstream.
- It bypasses the digestive metabolism, minimizing loss of functional ingredients, making it suitable for emergency medicines like angina treatment.
- Oral mucosa boasts approximately 4,000 times greater permeability compared to the epidermis, making it suitable for water-soluble low-molecular-weight substances. Research results indicate the application of glutathione through the oral mucosa.

2. Supply of Glutathione to the Body: Glutathione (Netherlands)
- Glutathione is a potent antioxidant formed through the synthesis of three amino acids (glutamate, cysteine, glycine) within the cell.
- It serves as a potent intracellular antioxidant and is used in medicine as a remedy for liver toxicity and drug poisoning.
- It aids in skin whitening by inhibiting tyrosinase, a key enzyme involved in melanin synthesis, and serves as a key ingredient in glutathione injections.
- It participates in both antioxidative and metabolic processes in the body, providing advantages such as detoxification, antioxidation, anti-inflammatory effects, liver cell protection, cellular toxicity prevention, and aging and dementia prevention.

3. Promotion of Glutathione Synthesis in the Body: L-Cysteine
- [L-Cysteine]: L-Cysteine, a sulfur-containing amino acid, acts as a precursor to glutathione within cells and is an essential element for glutathione synthesis.
- Compared to other amino acids required for glutathione synthesis, such as glutamate and glycine, L-Cysteine has a lower dietary intake, making it susceptible to deficiency.
- L-Cysteine promotes glutathione synthesis and has an impact on metabolism and skin whitening (inhibition of melanin pigment).

4. Inhibition of Glutathione Depletion in the Body: Vitamin C, Vitamin E, Milk Thistle 4.1. Vitamin C
- Vitamin C is an exogenous antioxidant, forming a non-enzyme-based antioxidative system within cells along with glutathione and vitamin E.
- After antioxidative activity, it contributes to the regeneration of oxidized vitamin E, extending the antioxidative effect.
- The supplementation of vitamin C has been shown to increase the quantity of glutathione in red blood cells.

4.2. Vitamin E
- Vitamin E, an exogenous antioxidant, forms a non-enzyme-based antioxidative system in conjunction with glutathione and vitamin C.
- It inhibits cellular membrane oxidation by active oxygen, and in cases of deficiency, cellular membranes are more easily oxidized, leading to cellular damage.
- Supplementation of vitamin E has been shown to increase the quantity of glutathione in red blood cells.

4.3. Milk Thistle
- Containing silymarin, which acts in phase I of the liver detoxification process, it functions as a robust antioxidant and liver protectant.
- It is presumed to compete with glutathione for consumption as an endogenous antioxidant, reinforcing the mechanism of glutathione enhancement.
- It has detoxifying, lipid peroxidation-inhibiting, and antioxidative effects, along with other functions such as improving skin redness and promoting skin whitening.

1. Systematic Formulation Design for Efficient Absorption and Utilization of Glutathione, the Core Component of Whitening Injection
- A formulation of reduced glutathione with 75% purity for direct supply of glutathione through yeast extract to ensure efficient absorption and utilization.
* Confirmed benefits include detoxification, antioxidation, anti-aging, and skin whitening. - Formulation including L-cysteine to enhance glutathione synthesis.
* Research reports confirm L-cysteine's promotion of glutathione synthesis and whitening effects.
- Formulation including Vitamin C, Vitamin E, and milk thistle to inhibit glutathione depletion.
* Research reports confirm the increase in glutathione quantity with Vitamin C supplementation.
* Research reports confirm the increase in glutathione quantity with Vitamin E supplementation.
* Research reports confirm the enhancement mechanism of glutathione with milk thistle (silymarin) intake.

2. A Synergistic Formulation Containing the Core Components of the Cellular Non-Enzymatic Antioxidant System
- The cellular non-enzymatic antioxidant system consists of a sequential system of [glutathione → Vitamin C → Vitamin E].
* Vitamin C recycles oxidized Vitamin E after antioxidation, and glutathione recycles oxidized Vitamin C.
- A formulation of glutathione, Vitamin C, and Vitamin E aims to achieve efficient antioxidation.

3. Achieving Antioxidation and Skin Beauty Simultaneously with a 2in1 Ingredient Setting
- Four core components have reported benefits in antioxidation and skin whitening.
* Glutathione, L-cysteine, Vitamin C, Vitamin E.

4. Rapid and Lossless Delivery of Functional Ingredients through Orally Dissolving Film (ODF)
- Direct delivery of functional substances through the oral mucosa, which has permeability about 4,000 times that of the epidermis.
- The process doesn't involve digestion and metabolism, resulting in minimal nutrient loss and fast absorption.

5. Review of Dr. LYUH ESTHER's Formulation and Bioavailability
- Dr. LYUH ESTHER: Preventive Medicine Doctor, Family Medicine Specialist at Seoul Medical School.
- Evaluation of the nutritional, preventive medicine significance, and potential risks of the product's formulation.
- Comparison and assessment of the working mechanism and bioavailability of the product with glutathione intravenous injections prescribed in family medicine.

6. Individual Packaging for Preventing Oxidation of Functional Ingredients & Convenience of Carrying and Consumption
- Individual film packaging within the case to prevent oxidation of functional ingredients and enhance portability.
- Pleasant lemon flavor upon attachment to the oral mucosa for enhanced consumption convenience.

- Those looking for foods that promote liver health and antioxidative effects. 
- Those seeking skin whitening through antioxidative effects. 
- Those desiring a brighter skin tone by addressing freckles or pigmentations. 
- Those searching for glutathione products with increased absorption in film form instead of capsules.