LYUH ESTHER LUTEIN ZEAXANTHIN DIRECT RS2

Daily Intake: 1 sheet (335mg)

※ % Nutritional Value: Percentages of the daily nutritional value 

① Lutein Zeaxanthin Complex Extract (Daehan Chemtech Co., Ltd., No. 2018-4): An individually recognized ingredient that helps maintain macular pigment density and eye health.

- In human eyes, only two types of carotenoids, lutein and zeaxanthin, are found.

- Lutein and its isomer, zeaxanthin, absorb high-energy short-wavelength light, protecting the photoreceptor cells in our eyes.

- The macular pigment in the retina is composed of lutein, with zeaxanthin located at the center.

- Since lutein and zeaxanthin are not synthesized in the human body, they must be supplemented through diet.

- Characteristics of the ingredient:

  1. Xanmax®: 8 international patents in 5 countries (USA, Japan, India, Australia, Europe)

    1) High-purity extraction technology 2) Low-temperature extraction below 60 degrees Celsius minimizes the formation of oxidation products.

    3) Environment-friendly hot air drying process, which emits no pollutants.

  2) High-quality marigold ingredients used: HALAL, KOSHER certified.

  3) Seed to Formulation: From seed cultivation to raw material production, Katra Phytochem strictly controls quality throughout the entire process.

  4) Only a very small amount, 0.003 kg, is obtained from 1 kg of marigold flowers – a rare ingredient.

  5) Katra Phytochem: Certified by NSF, FSSC22000, KFDA/USFDA, ISO 9001.

- [Human Trials] After 6 months of consumption by 60 individuals aged 45-65, macular pigment density increased by +44.9%.

- Recommended daily intake: Total of 10 to 20 mg/day of lutein and zeaxanthin.

- Composition: 20 mg of lutein zeaxanthin per tablet.

② AREDS2 Clinical Trials formula: A blend of four ingredients clinically proven effective by the National Eye Institute (NEI) in the USA.

- The AREDS2 clinical study conducted by the National Eye Institute observed the intake and effects of specific nutrients in 4,203 patients with macular degeneration/cataracts.

- Participants received lutein 10mg, zeaxanthin 2mg, zinc 80mg, vitamin C 500mg, vitamin E 400IU, and copper 2mg, resulting in a 25% reduction in the risk of severe macular degeneration.

- Our product closely matches the maximum allowable amounts of these four proven ingredients as specified by the [Food and Drug Administration minimum functional content].

  Composition: Vitamin C 20mg, Vitamin E 2.5mg, zinc oxide 2mg, copper gluconate 0.2mg.

③ Five additional ingredients that may aid eye health: bilberry, blueberry, grape extract, cassia seed extract, and acerola.

- These supplementary ingredients, backed by research results for eye diseases such as cataracts and macular degeneration, were selected based on SCIE papers.

- Bilberry extract powder: Significant improvement in HFC-1 values after 12 weeks of intake of 240mg bilberry extract by 109 individuals.

  [SCIE, source] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146147/

- Acerola (Vitamin C 17%): Vitamin C delays the onset of cataracts in patients who have undergone vitrectomy.

  [SCIE, source] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602486/

- Blueberry: In vitro, anthocyanin extracts reduce oxidative stress and increase antioxidant enzymes, inhibiting macular degeneration.

  [SCIE, source] https://pubs.acs.org/doi/abs/10.1021/acs.jafc.7b06135

- Red wine: Polyphenols found in grapes are involved in minimizing eye defects such as cataracts, diabetic retinopathy, and macular degeneration.

  [SCIE, source] https://www.sciencedirect.com/science/article/abs/pii/S1382668916303210

- Cassia seeds: Oral administration of cassia seed leaves to a mouse model for five days protected against cataracts by regulating the ubiquitin-proteasome pathway.

  [SCIE, source] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130452/

① South Korea's first health functional food Lutein Zeaxanthin Film (ODF)

- This is the first functional lutein zeaxanthin ODF in South Korea, containing 20 mg of lutein zeaxanthin per film (18.18 mg of lutein and 1.82 mg of zeaxanthin).

- Uses the individually recognized ingredient No. 2018-4, Lutein Zeaxanthin Complex Extract, and its stability confirmed by shelf life testing.

- Advantages of the film form:

  1) Direct absorption of functional components into the capillaries through the oral mucosa.

  2) As it bypasses gastric metabolism, there is less loss of active ingredients, and absorption into the body is faster.

  3) Particularly suitable for application of water-soluble low-molecular substances, the oral mucosa has about 4000 times higher permeability compared to the epidermis.

  4) Lutein's molecular weight (564 mol) and its liposoluble condition suit mucosal absorption, and its low daily intake (20mg) is optimal for rapid absorption and pharmacological effect.

② Maximum daily intake of lutein zeaxanthin approved by the MFDS (20 mg/day)

- The periphery of the retinal macular pigment is composed of lutein, and the center contains zeaxanthin.

- Lutein and zeaxanthin absorb high-energy short-wavelength light, protecting the photoreceptor cells.

- Ingredient advantages: ■ International patents in five countries (Australia, Japan, USA, India, Europe) ■ Low-temperature extraction under 60 degrees to minimize damage to ingredients, high-purity extraction, environmentally friendly drying method.

- Human trial results: A study involving 60 adults aged 45-65, consuming 20 mg/day of Lutein Zeaxanthin Complex Extract for 180 days, showed a +44.9% increase in macular pigment density.

③ Blend of five supplementary ingredients beneficial for eye health: bilberry, blueberry, grape, cassia seed, and acerola.

- These were chosen based on SCIE papers for their research results on eye diseases such as cataracts and macular degeneration.

- Bilberry extract powder: Significant improvement in HFC-1 values after 12 weeks of intake of 240 mg bilberry extract by 109 individuals.

  [SCIE, source] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146147/

- Acerola (Vitamin C 17%): Vitamin C delays the onset of cataracts in patients who have undergone vitrectomy.

  [SCIE, source] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602486/

- Blueberry: In vitro, anthocyanin extracts reduce oxidative stress and increase antioxidant enzymes, inhibiting macular degeneration.

  [SCIE, source] https://pubs.acs.org/doi/abs/10.1021/acs.jafc.7b06135

- Red wine: Polyphenols found in grapes are involved in minimizing eye defects such as cataracts, diabetic retinopathy, and macular degeneration.

  [SCIE, source] https://www.sciencedirect.com/science/article/abs/pii/S1382668916303210

- Cassia seeds: Oral administration of cassia seed leaves to a mouse model for five days protected against cataracts by regulating the ubiquitin-proteasome pathway.

  [SCIE, source] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130452/

Those who wish to easily consume lutein and zeaxanthin with just one tablet a day.  

Those who want to prevent eye diseases such as cataracts and macular degeneration with a daily tablet.  

Those who feel eye fatigue as they age.  

Those in occupations like office workers and students who are experiencing difficulties due to eye health issues.  

Those who have had difficulty experiencing effects from typical softgel capsules.