LYUH ESTHER STRESS CARE

Effect

Net Contents

1,000 mg * 60 tablets (60 g)

Quantity per Carton

72

Ingredients & Contents  

Magnesium Oxide, L-Theanine, Vitamin C, Zinc Oxide, Vitamin B6 Hydrochloride, Microcrystalline Cellulose, Dextrin, Black Garlic Extract Powder, Silicon Dioxide, Magnesium Stearate, Hydroxypropyl Methylcellulose, Other Processed Products, Sage Extract Powder, L-Tryptophan, Choline Hydrogen Citrate, Glycerin

Precautions for Consumption

- Be cautious when consuming caffeinated beverages (coffee, black tea, green tea, etc.). 

- Pregnant women, breastfeeding women, children, and patients before or after surgery should be cautious when taking this product. 

- If any adverse reactions occur, stop consumption and consult a healthcare professional. 

- People with specific conditions or those consuming in excess may experience allergic reactions, so please check the ingredients and recommended dosage before consumption. 

- Be careful as the packaging may cause injury when opening or consuming the product.

Intake Amount & Method

Take 2 tablets once a day with plenty of water

Expiration Date 

24 months from the date of manufacture

Nutrition Facts

Daily intake: 2 tablets (2,000 mg)

※ % Daily Value: The percentage of the daily nutrient reference value

Main Ingredient

① Theanine: Increases GABA production, increases serotonin to reduce glutamate

- Theanine is a functional ingredient for relieving anxiety by reducing the excitatory neurotransmitter glutamate.

- After ingestion, it passes through the blood-brain barrier within 1 hour and maintains its concentration for 5 hours.

- Related mechanisms

1) Increase in GABA synthesis → Decrease in norepinephrine → Decrease in glutamate

2) Increase in serotonin → Decrease in norepinephrine in the locus coeruleus → Decrease in glutamate

3) Inhibition of glutamate receptor binding by glutamine → Decrease in glutamate

4) Other: Reduction in corticotropin and corticotropin-releasing factor → Induces decrease in cortisol and serotonin

- Daily intake: 200-250mg

- Content per serving: 250mg (maximum daily intake) ▷ Source: India

② Magnesium: Activates GABA action, promotes serotonin signaling, reduces glutamate, and other mechanisms related to neural health

- Magnesium is a key nutrient for stress response regulation and neuroinhibition, inducing brain health through various mechanisms.

- Related mechanisms (https://www.mdpi.com/2072-6643/12/12/3672):

1) Enhances GABA action

2) Directly promotes serotonin cell signaling

3) Assists tryptophan hydroxylase involved in serotonin synthesis

4) Blocks glutamate receptors

5) Reduces adrenocorticotropic hormone (ACTH) → Decreases cortisol

6) Promotes brain-derived neurotrophic factor (BDNF) expression

- Daily intake: 94.5mg-315mg

- Content per serving: 315mg (100%) ▷ Source: Japan

③ Vitamin B6: Supports GABA and serotonin production when taken alone or in combination with magnesium

- Vitamin B6 is a well-known ingredient for alleviating anxiety/depression through human clinical studies, especially when taken alone in high doses or with magnesium.

- Related mechanisms (https://www.liebertpub.com/doi/abs/10.1089/152460900318623):

1) Produces GABA and serotonin, influencing selective regulation

2) Activated by magnesium intake

- Daily intake: 0.45mg-67mg

- Content per serving: 1.5mg (100%) ▷ Source: DSM Ingredients, Germany

④ Vitamin C: Activates GABA receptors, reduces glutamate

- Vitamin C is generally consumed for cortisol (stress) regulation, but its role in GABA/glutamate regulation has been studied as well.

- Related mechanisms (https://www.mdpi.com/2072-6643/9/7/659):

1) Activates GABA receptors

2) Inhibits binding to glutamate receptors (NMDA), preventing neural excitation

3) Other: Regulates adrenal function (controls catecholamine and cortisol synthesis, adrenal suppression effect)

- Daily intake: 30mg-1000mg

- Content per serving: 30mg (30%) ▷ Source: United Kingdom

⑤ Zinc: Acts on GABA, serotonin, and glutamate systems

- While human clinical data on zinc deficiency is limited, low zinc levels have been observed in patients with anxiety, and related mechanisms are known.

- Related mechanisms (https://pubmed.ncbi.nlm.nih.gov/37364014/):

1) Reduces anxiety through its action on GABA, serotonin, and glutamate systems

- Content per serving: 8.5mg (100%)
▷ Source: United States

⑥ Other Ingredients: Components that may support the action of Theanine

- Black Garlic Extract 100mg (SAC 1mg): Reduces cortisol, normalizes serotonin/dopamine/norepinephrine levels, prevents dopamine depletion
  ▷ Source: Netherlands, contains 1% SAC

- GABA (Other Processed Products): Helps increase GABA synthesis from Theanine
  ▷ Source: South Korea

- St. John's Wort (Western Pepperwort): Helps increase serotonin levels
  ▷ Source: Spain

- Tryptophan: A precursor for serotonin synthesis
  ▷ Source: China

- Choline: A precursor for phosphatidylcholine, increases phospholipids and synapses in the brain
  ▷ Source: Italy

Selling Point

① Chronic anxiety in modern people is alleviated, and concentration is improved with [Theanine + 5 Types of Vitamins/Minerals + 1mg SAC]

- This product is generously combined with functional ingredients like Theanine to create a synergistic effect for alleviating anxiety and depression through [GABA production and increased serotonin levels].

- Theanine increases the concentration of the inhibitory neurotransmitters GABA and serotonin, reducing glutamate to relieve depression/anxiety.

- Theanine's effects can be compared to those of benzodiazepine antidepressants and serotonin reuptake inhibitors.
※ The product contains the maximum daily intake of 250mg, equivalent to 10 cups of red tea, making it easy to consume two tablets for the same effect.

② Key nutrient for stress response regulation 'Magnesium' 100% + 'Vitamin B6' 100% proven through human clinical trials

- Magnesium activates GABA action and serotonin signaling, helping the synergy of Theanine, while also promoting adrenal regulation and BDNF expression.

- Zinc, when taken with magnesium, has been proven through human clinical trials to alleviate anxiety and depression. 

※ 100% of the recommended daily intake is combined to support Theanine and maximize the effects of magnesium and zinc.

③ 'Vitamin C' 30% to regulate cortisol, GABA, and glutamate at once + 'Zinc' 100% for preventing anxiety at low levels

- Vitamin C not only regulates overly sensitive adrenal function due to stress but also helps activate GABA and reduce glutamate.

- Zinc, which is found to be significantly low in patients with anxiety/depression, works on the GABA, serotonin, and glutamate systems to help. 

※ The combination of 30% Vitamin C and 100% Zinc enhances the synergistic effect.

④ Restoring balance in the nervous system and preventing dopamine depletion with Phytochemical SAC 1mg + 4 other brain health ingredients

- SAC 1mg, a phytochemical found in black garlic, provides super antioxidant and neuroprotective effects.

- Ingredients like 'GABA,' 'St. John's Wort,' and 'Tryptophan' help increase GABA and serotonin levels.

- 'Choline,' a precursor substance for phosphatidylcholine, promotes brain health by increasing phospholipids and synapses in the brain.

Recommended Target

- Office workers showing chronic depression, anxiety, and obsessive symptoms

- Students struggling with concentration due to excessive stress

- Those who want to enjoy the calming effects of green tea without caffeine

- Those who want to achieve calmness in life through immediate relaxation

- Those suffering from anxiety, depression, stress, etc.