LYUH ESTHER SUPER HEALTH CURCUMIN 2.0

2. Improves of rheumatoid arthritis

3. Antioxidant

Daily Intake: 1 tablet (500mg)

※ % Nutritional Value: Percentages of the daily nutritional value

1. Anti-inflammatory mechanism of curcumin

① Inhibition of inflammatory transcription factor (NF-kB), inhibition of inflammatory cytokines (tumor necrosis factor, IL-1, IL-6)

② Inhibition of inflammatory enzymes (COX-2, COX-5)

※ Various health effects have been proven for rheumatoid arthritis, ulcerative colitis, eye disease, liver health, and brain health due to its extensive anti-inflammatory mechanism.

2. Anticancer mechanism of curcumin

① Regulation of DNA methylation *DNA methylation: Plays an important role in the development of cancer → Curcumin regulates DNA methylation to suppress the expression of cancer.

② Regulation of histone modification *Histone modification: An epigenetic event closely related to DNA methylation, contributing to the regulation of cell replication and accessibility.

③ Regulation of non-coding and RNA expression *miRNA affects metabolism, proliferation, differentiation and suicide of cancer cells → Curcumin regulates non-coding and RNA protein expression

1) Turmeric Extract: Super health effects through anti-inflammatory and anti-cancer mechanisms

– This ingredient is a premium curcumin material from SABINSA, completed with the technology of Arribaio H&B Co., Ltd., a recognized individual turmeric extract material.

– Unlike general food ingredients, its marker substances are managed according to the standards of the Korea Food & Drug Administration, with proven efficacy and safety.

– Functionality: Can help improve muscle strength / Developed to enhance health effects related to sarcopenia in seniors.

– Special Features:

  1) Patent holder: Patent No. 10-2108868 – Composition for improving muscle function

  2) Uses SABINSA ingredient: A valuable ingredient obtained by producing only 15KG from 1000KG of raw turmeric (with over 95% curcumin content)

  3) SABINSA ingredient certification: HALAL certified, KOSHER certified / Ingredient from India

  3) Particle size: Managed to be under 1000nm (refer to attachment)

– Human application test: In a study of 61 men and women aged 50-85 with muscle weakness, consuming turmeric extract (250MG/day) for 12 weeks resulted in a significant increase in muscle strength and a significant decrease in physical activity measurement (TUG, performance time).

– Blend content: 250mg (curcumin 102.75mg)

2) Liposomal Vitamin C: Antioxidant synergy & absorption rate complement when taken with curcumin

– A major drawback of curcumin is its very low absorption rate in the body, no matter how much is consumed.

– By mixing Vitamin C, which can strengthen the antioxidant effect of curcumin, with liposome ingredients, its disadvantages can be compensated.

– [Animal study] In diabetic rats, the combined intake of curcumin and Vitamin C showed an antioxidant synergy, reducing blood sugar and lipid levels.

  (https://pubmed.ncbi.nlm.nih.gov/17148847/)

– Special Features: 1) Uses British DSM Vitamin C 2) DSM Vitamin C reprocessed into liposomes in Korea 3) Vitamin C purity 75%

3) Quercetin & Resveratrol (Red Wine Extract Powder): Antioxidant synergy ingredients confirmed by SCIE papers

– Quercetin, a flavonoid found in red onions and kale, is known for its effects on antioxidants, blood sugar enhancement, and heart disease.

  [Human application test]: In 5 patients who had surgery for colon cancer, the combined intake of curcumin and quercetin for 6 months reduced the size of the cancer.

  (https://www.sciencedirect.com/science/article/abs/pii/S1542356506002783)

  [Cell experiment]: The combined treatment of curcumin and quercetin inhibited Staphylococcus aureus/Pseudomonas aeruginosa, which plays a major role in infected wounds.

   Ingredient documentation: German origin, purity over 95%

– Resveratrol, a phytochemical found in red grapes, is known for lowering blood lipid levels and having a strong antioxidant effect.

  [Cell experiment]: The combination of curcumin and resveratrol exhibited synergistic antioxidant effects.

   Ingredient documentation: Australian origin, purity over 5% (Ingredient name: Red Wine Extract Powder)

4) Boswellia, Apigenin, Catechin: Anti-inflammatory/anti-cancer synergy ingredients confirmed by SCIE papers

– Boswellia, extracted from the frankincense tree, is known for its anti-inflammatory effects, especially for arthritis.

  [Human application test] In 54 patients with osteoarthritis, [curcumin + boswellia] pills were more effective than celecoxib (medication).

  (https://pubmed.ncbi.nlm.nih.gov/24002213/)

   Ingredient documentation: Indian origin, purity over 65%, HALAL/KOSHER certified (Ingredient name: Boswellia Extract Powder)

– Apigenin, a flavonoid found in parsley, celery, and onions, has been extensively researched for its particularly anti-cancer effects.

  [Cell experiment] [Curcumin + apigenin] induced apoptosis in lung cancer cells through a synergistic anti-cancer effect.

  (https://www.sciencedirect.com/science/article/abs/pii/S0300908413000679)

   Ingredient documentation: Domestic (Ingredient name: Plant Mixed Extract Powder)

– Catechin, a polyphenol primarily found in green tea, is known for its strong antioxidant and anti-cancer effects.

  [Cell experiment] [Curcumin + EGCG] induced cell cycle arrest in cancer cells, inhibiting lung cancer cells.

  https://www.mdpi.com/1422-0067/14/6/12023

   Ingredient documentation: Indian origin, catechin purity over 75%

1) Uses curcumin, one of the world’s top ten anti-cancer and anti-inflammatory nutrients, as an individually recognized ingredient with proven efficacy and safety

– Curcumin is a super health nutrient with strong anti-inflammatory and anti-cancer mechanisms, introduced in over 600 articles by the National Institutes of Health (NIH) in the United States.

– Holds Patent No. 10-2108868 (Composition for improving muscle function)

– Uses premium curcumin ingredients from SABINSA in India (HALAL, KOSHER certified), completed with the technology of Arribaio H&B, a domestic manufacturer

– Functionality: Can help improve muscle strength

    Human trials have confirmed the effect of improving muscle strength in subjects with muscle weakness

2) ‘Liposomal Vitamin C’ enhances the antioxidant effect of curcumin and compensates for its disadvantage (low absorption rate)

– Vitamin C, when taken in conjunction with curcumin in animal tests, showed an antioxidant synergy with a blood sugar control effect

– Combines stable and highly absorbable liposomal vitamin C to consume two antioxidant nutrients at once

3) Two types of plant nutrients that further enhance the antioxidant effect when taken in conjunction with curcumin

– [Human trial] ‘Quercetin’, which showed an antioxidant and anti-cancer synergy effect when taken in conjunction with curcumin

– [Cell experiment] ‘Resveratrol’, which showed a synergistic antioxidant effect when taken in conjunction with curcumin

4) Three types of plant nutrients that enhance the anti-inflammatory and anti-cancer effects when taken in conjunction with curcumin

– [Human trial] ‘Boswellia’, which showed an anti-inflammatory effect in osteoarthritis patients when taken in conjunction with curcumin

– [Cell experiment] ‘Apigenin’, which induced apoptosis in lung cancer cells when treated in conjunction with curcumin

– [Cell experiment] ‘Catechin’, which induced cell cycle arrest in cancer cells when treated in conjunction with curcumin

Those who want to consume functional curcumin with confirmed efficacy and safety.

Those who want to consume plant nutrients with confirmed synergistic effects with curcumin all at once.

Those who wish to consume super anti-cancer and anti-inflammatory nutrients with just one pill a day.

Those who find it difficult to manage their condition due to stress.

Seniors who struggle with physical management due to decreased muscle strength.