LYUH ESTHER NMN PHYTOS

2. Helps maintain vitality and focus

3. Cancer prevention

– NMN (Nicotinamide Mononucleotide) is a direct precursor for NAD+ synthesis, and an increase in NAD+ levels through oral intake in the human body has been confirmed

– What is NAD+? It is a coenzyme present in all cells of the human body that regulates bodily functions through redox reactions 1) Activation of SIRTUIN genes 2) Repair of DNA damage 3) Regulation of telomere length 4) Promotion of energy production in mitochondria, helping our bodies function normally and prevent aging

– Ingredient proposed by Dr. David Sinclair, a leading authority in the field of aging at Harvard Medical School, which has gained worldwide recognition

– NAD+ levels decrease to less than half of those in individuals in their 20s by the age of 50, leading to 1. Acceleration of aging 2. Increased probability of cancer 3. Decreased energy 4. Increased likelihood of degenerative muscle and neurological disorders

– Related Mechanism: The Role of NAD+ in the Human Body

1) Coenzyme in Energy Production: NAD+ is utilized in the processes of obtaining energy from sugars and breaking down fats for energy.

2) Consumption by Sirtuins: 1. Cellular homeostasis and apoptosis 2. Gene stabilization 3. Regulation of insulin metabolism

3) Consumption by PARP Enzymes: 1. Repair of damaged DNA 2. Generation of mono-ADP proteins that attach to damaged DNA

4) Regulation of Telomere Length: When telomeres shorten and unravel, the genetic code may be misinterpreted, leading to cell modification or death

② The two components that inhibit the overactivity of PARP/NADase and help SIRTUIN consume NAD+: Quercetin, Apigenin

– These ingredients help ensure that NAD+ increased through NMN can be 100% consumed by the longevity gene SIRTUIN.

– Key coenzymes that utilize NAD+ as a substrate, including [SIRTUIN, PARP enzymes, NADase], compete with each other for NAD+.

– Abnormal activation of PARP enzymes and NADase (CD38, CD157, SARM-1) can further worsen aging; therefore, NAD+ increased through NMN should be consumed by SIRTUIN rather than PARP/NADase to reap the benefits of longevity supplements

③ Synergistic Ingredients for Promoting SIRTUIN Activation: Pterostilbene, Quercetin, Apigenin + Betaine + Vitamin D

– Various phytochemicals have been researched for SIRTUIN activation, and a combination of ingredients with strong supporting evidence has been selected

– With aging, the concentration of NAD+ decreases, reducing the energy production capacity in our mitochondria, thereby promoting aging and cancer.

– NAD+ is competitively consumed by 1. SIRTUIN, 2. PARP, and 3. NADase (CD38, CD157, SARM-1). Reducing PARP/NADase overactivation and enhancing SIRTUIN activation can activate various genes that promote a healthy biological age.

– This product is formulated with three mechanisms in mind: 1) The direct precursor of NAD+, 2) Reducing PARP/NADase overactivation, and 3) Enhancing SIRTUIN activation.

✓ Increase in NAD+ concentration: By consuming naturally derived NMN and vitamin B3, the concentration of NAD+ in the body is increased.

✓ Reduction in PARP/NADase overactivation: Quercetin and apigenin help ensure NAD+ is fully consumed by SIRTUIN.

✓ SIRTUIN activation: Pterostilbene, quercetin, apigenin, betaine, and vitamin D promote the activation of SIRTUIN.

② Optimal Ingredient for Increasing NAD+ Levels: NMN

– Various substances such as tryptophan, niacin, niacinamide, and NR have been studied to increase NAD+ levels, but NMN has been identified as the closest substance to NAD+ in the body, effectively boosting its concentration.

– When NMN increases NAD+ levels, it provides four key benefits: 1) Activation of SIRTUIN, 2) PARP enzyme (DNA repair), 3) Regulation of telomere length, and 4) Mitochondrial energy production. These benefits can reverse biological age by more than 10 years and help maintain the vitality and focus of your 20s.

Safely consumed through naturally derived NMN

– Harvard Medical School professor’s top-recommended ingredient

③ Five Ingredients that Inhibit the Overactivation of PARP/NADase, Promoting Aging, and Activate SIRTUIN to Reverse Biological Age

– It was previously thought that merely increasing NAD+ levels would activate SIRTUIN; however, recent studies have shown that the overactivation of PARP and NADase hinders SIRTUIN from consuming NAD+ and promotes aging and cancer.

– Quercetin and apigenin inhibit the overactivation of PARP/NADase, allowing NAD+ to be effectively utilized by SIRTUIN.

– Betaine contributes to DNA stabilization through methylation, while pterostilbene activates SIRT1, acting as a synergistic ingredient.

✓ Four phytochemical ingredients aimed at achieving the ultimate goal of SIRTUIN activation

✓ Enjoy countless health benefits from naturally derived phytochemicals

For those who want to reverse their biological age by more than 10 years and regain the vitality and focus of their 20s

For those who want to experience the 21st-century elixir of youth in the form of a film

For those who want to maintain a healthy body by consuming various phytochemicals

For those who are seeking a real NMN product with noticeable effects