Brain Probiotics

Effect

- Supports memory and cognitive function in aging adults

- Helps increase beneficial gut bacteria and reduce harmful bacteria

- Promotes regular, comfortable bowel movements and overall gut health

Net Contents

Quantity per Carton

Ingredients & Contents  

Probiotic Complex of L. mucosae NK41 and B. longum NK46 (NVP-2106), Maltodextrin, Cottonseed Oil Powder, Bamboo Sap Extract Powder, Phosphatidylserine, L-Theanine, Turmeric Extract Powder, Ginkgo Biloba Extract, Vitamin B12 Blend (Vitamin B12, Maltodextrin, Trisodium Citrate, Citric Acid), Folic Acid, Vitamin B6 Hydrochloride

[Capsule Base] Hydroxypropyl Methylcellulose, Purified Water, Titanium Dioxide (Colorant), Carrageenan, Sorbitan Fatty Acid Ester, Magnesium Chloride, Glycerin, Potassium Chloride

* Contains Milk, Soy

Precautions for Consumption

- Infants, young children, pregnant women, and breastfeeding women should avoid consumption.

- Consult a healthcare professional if you have specific conditions (such as allergies or short bowel syndrome) or if you are taking any medications.

- Ensure that children follow the recommended daily intake and do not consume the product unsupervised.

- Do not exceed the recommended dosage.

Intake Amount & Method

Take 1 capsule once daily with plenty of water

Expiration Date 

18 months from the date of manufacture

Nutrition Facts

Per Daily Intake: 1 capsule (450 mg)

※ % Daily Value: Percentage of the daily recommended intake

Main Ingredient

1. What are Probiotics?

- Live beneficial bacteria that, when consumed, have positive effects on health

- Once they reach and settle in the intestines, probiotics produce lactic acid, making the intestinal environment more acidic

- In an acidic environment, harmful bacteria that cannot survive decrease, while beneficial bacteria that thrive in acidity increase, helping to maintain a healthy gut environment

2. MFDS-Approved Individually Recognized Ingredient – Probiotic Complex of L. mucosae NK41 and B. longum NK46 (NVP-2106) (No. 2025-15)

- May help improve cognitive function that has declined due to aging

- May help increase beneficial bacteria, suppress harmful bacteria, support smooth bowel movements, and promote intestinal health

Selling Point

✓ Human Clinical Trial (12 Weeks, Korean Participants)- 

Improved up to 9 major clinical cognitive indicators:

ADAS-Cog13 Total Score, ADAS-Cog13 Memory Score, ADAS-Cog13 subtests: Delayed Word Recall, Word Recall, CNT subtests: Attention Accuracy, Attention Errors, Omission Errors, CNT Reaction Time, Blood Aβ 42/40 ratio improvement

- Unlike other ingredients that show only temporary symptom relief, Esther Lyuh Brain Probiotics target the root cause of cognitive decline through: Improvement of gut microbiome balance, Reduction of inflammatory cytokines, Reduction of blood amyloid-beta

✓ Patents: 34 patents across 28 countries

✓ Publications: 5 SCIE-indexed scientific papers

✓ Safety: Registered and recognized by EFSA (Europe), Canada Monograph, and IDF (International Dairy Federation), Meets GRAS, EFSA, and MFDS safety criteria, Proven non-toxic with no hemolytic activity or antibiotic resistance risks

✓ Individually Recognized Ingredient: Latest MFDS-approved cognitive health probiotic ingredient (as of April 2025)

✓ Animal Studies

1) Improved cognitive function, reduced depressive behavior, decreased hippocampal inflammation, increased BDNF expression

2) Reduced colitis markers, increased bacterial diversity, improved gut microbiome composition

3) Improved cognitive decline, reduced hippocampal Aβ accumulation, increased BDNF and Claudin-5, decreased NF-κB activation

4) Improved cognitive impairment, increased hippocampal BDNF and p-CREB, decreased NF-κB, TNF-α, LPS

5) Enhanced cognitive and anti-inflammatory effects when probiotics were taken in combination rather than alone

6) Significant improvement in depression/anxiety behavior, reduced NF-κB and Iba1+ activation, increased BDNF, improved gut inflammatory markers

→ Quick Key Points (Easy Highlights)

1. One capsule a day for total brain + gut health

2. Uses MFDS-approved B. longum strains (officially recognized functional probiotics)

3. 4-in-1 Functional Health Supplement:
① Supports cognitive function impaired by aging
② Helps increase beneficial bacteria & suppress harmful bacteria
③ Supports smoother bowel movements
④ Promotes overall gut health

4. Internationally recognized, clinically proven safe probiotics

5. 28-country patented strains providing smart dual care for the gut–brain axis

6. High-potency formula with 10 billion CFU guaranteed

7. Most clinical results in Korea — significant improvements in 9 cognitive and gut-related indicators

8. Small, easy-to-swallow capsule designed for convenience and stability

Recommended Target

- For those who struggle to recall words during conversations

- For those who often forget things easily

- For those who frequently lose personal items

- For those who want to care for both gut health and brain health at the same time